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Is Tequila a Depressant? The Truth Behind the Tequila Upper Myth

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Cathy Bilotti - Clinical Director - Simple Path Recovery

Cathy Bilotti, M.ED., LMHC

Clinical Director

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Table of Contents
Article SummaryTequila is a depressant. Like every alcoholic drink, it gets its effects from ethanol, which slows the central nervous system. The “tequila upper” feeling comes from alcohol’s early stimulant-like effects, the party setting, and caffeinated mixers, not from anything unique to tequila.

Tequila is a depressant. Like beer, wine, and every other alcoholic beverage, it gets its effects from ethanol, which slows central nervous system activity. You may hear that tequila is an upper, a drink that gives people energy instead of slowing them down, but that idea is a myth.

If you have ever wondered why the myth is so popular, a few tequila shots can make a person feel loose, talkative, and full of confidence. Alcohol can produce both stimulant-like and sedating effects, with the early lift often occurring as blood alcohol rises [1]. That does not make tequila a different kind of alcohol.

If drinking has started to feel hard to control, information about alcohol rehab in Pompano Beach is available when you want it.

Is Tequila a Depressant?

A man pouring sparkling water with lime in his home kitchen.

Tequila is a distilled liquor made from the agave plant, and its main intoxicating ingredient is the same ethanol found in other alcoholic beverages. Alcohol is classified as a central nervous system depressant, even though its effects can include an early feeling of stimulation.

Depressants reduce brain activity. When people drink tequila, it can feel relaxing at first, but as a person keeps drinking, the slowing spreads to judgment, coordination, memory, and eventually breathing.

Tequila shares depressant effects with sedatives and opioids, although they are different drug classes. Our guide to what are depressant drugs explains how alcohol fits alongside them and why the group shares so many risks.

A Shot of Tequila Has the Same Alcohol as a Beer

The amount of alcohol and how quickly it is consumed matter more than the drink’s name. Food, medications, body size, and individual sensitivity also affect the response.

The National Institute on Alcohol Abuse and Alcoholism explains that a standard drink in the United States contains about 14 grams of pure alcohol [2]. That is the amount in a 12-ounce beer at 5 percent alcohol, a 5-ounce glass of wine at 12 percent, or a 1.5-ounce shot of distilled spirits at 40 percent.

NIAAA lists tequila by name among those distilled spirits. A 1.5-ounce shot of 80-proof tequila holds about the same alcohol as a 12-ounce beer at 5 percent or a 5-ounce glass of wine at 12 percent. Larger pours and stronger drinks contain more.

For example, a tequila sunrise or a margarita made with sweet mixers may hold more than one standard drink, depending on the recipe. Tequila shots also go down quickly, so more alcohol can be consumed in a short time than with a beer that is sipped.

For a broader look at alcohol’s effects in general, our post on whether alcohol is a stimulant or depressant covers the science behind the confusion.

Why Tequila Feels Like an Upper

Several things combine to make tequila feel like a stimulant, even though it is not one. Understanding the difference between a true stimulant and alcohol helps explain what is really happening.

The first is alcohol’s changing effects on the brain. It can produce both stimulation and sedation, and the balance varies with dose, timing, and the person. Lowered inhibitions may contribute to feeling social or confident, but the early lift is not simply imaginary.

The second is the setting. Tequila is often served as shots at celebrations, which means music, a crowd, and a fast pace. People tend to expect a lively night, and expectations shape how a drink seems to feel.

The third is what tequila is mixed with. Caffeine is a stimulant, and mixing it with alcohol can make people feel more alert or less affected. The CDC warns that caffeine does not reduce alcohol’s effects on the body, so feeling energized does not mean judgment or reaction time has recovered [3].

What Tequila Does as Blood Alcohol Rises

As more alcohol is consumed, blood alcohol concentration rises and the depressant effect becomes clearer. Drowsiness, slower ability to react, poor coordination, trouble trying to focus, and memory gaps replace the early lift, and some people start feeling anxious or low as the effects wear off.

Heart rate and blood pressure can change as well, and the risk grows when alcohol is combined with opioids, as our post on how opioids affect blood pressure explains.

NIAAA warns that blood alcohol can keep rising even after a person stops drinking, because alcohol in the stomach and intestine continues to enter the bloodstream [4]. That is why someone who seems only tipsy can become dangerously impaired later, sometimes after they have stopped drinking and gone to sleep.

At high levels, alcohol intoxication can lead to loss of consciousness and can shut down areas of the brain that control breathing, heart rate, and temperature. NIAAA lists slow or irregular breathing among the critical signs of an alcohol overdose.

That slowed breathing has a medical name, explained in our post on respiratory depression. Call 911 immediately if an alcohol overdose is suspected, including when someone cannot be woken or is breathing slowly or irregularly. Stay with the person and do not assume they can sleep it off.

Why Mixing Tequila With Other Depressants Is Risky

Because tequila is a depressant, it adds to the effects of other depressants. NIAAA warns that combining alcohol with opioids, benzodiazepines, sleep aids, or even some over-the-counter antihistamines can cause an overdose even at moderate levels of drinking. These drugs and alcohol slow the same brain functions, so their effects stack.

The FDA also advises against drinking alcohol with benzodiazepines, since alcohol raises the risk of serious and life-threatening side effects. Our post on how long do benzos stay in your system explains why a dose from the day before can still matter.

The FDA’s review of benzodiazepine safety also found that misuse often involves alcohol and prescription opioids together, and that those combinations worsen the risk of serious harm, including overdose [5]. Mixing tequila with any of these drugs is a combination, not a single substance, and the danger depends on the total effect of everything taken.

Opioids carry the same risk. NIAAA warns that alcohol combined with opioids such as oxycodone or heroin can intensify suppression of vital functions, including breathing, and cause an overdose [4]. Our post answering are opioids depressants explains how opioids slow breathing, and why adding alcohol makes that more dangerous.

If you take any prescription medication, ask a pharmacist whether drinking is safe with it.

When Tequila Becomes a Pattern

An occasional drink is different from drinking that keeps growing. Over time, regular drinking can build tolerance, so a person needs more alcohol to feel the same effect. Signs that drinking may be turning into an alcohol use disorder include drinking more than planned, trouble cutting back, and continuing despite negative consequences for health, work, or mental health.

Recognizing a cycle like this, and taking time to reflect on drinking patterns, is often the first step. Anxiety, sleep problems, and strained relationships can all lead people to look more closely at how alcohol fits into their life. Benzodiazepines and opioids share many of alcohol’s risks, as our post on how benzodiazepines differ from opioids explains.

Frequently Asked Questions About Tequila

Is Tequila an Upper or a Downer?

Tequila is a downer, since it contains ethanol, the same depressant found in beer and wine, which slows the central nervous system. Alcohol can still produce stimulant-like feelings early on, alongside lowered inhibitions and the effects of the setting. Those feelings do not prevent impaired judgment, slowed reactions, or dangerous sedation.

Does Tequila Make You Sleepy or Awake?

Tequila can make you feel awake and talkative at first, but it is a depressant, so larger amounts usually bring drowsiness and slowed reactions. Alcohol can also disrupt sleep later in the night. If tequila is mixed with caffeine, a person may feel more alert while still being impaired by the alcohol.

Is Tequila Healthier Than Other Alcohol?

No type of alcohol is a healthy drink. A 1.5-ounce shot of 80-proof tequila contains about the same pure alcohol as a 12-ounce beer at 5 percent or a 5-ounce glass of wine at 12 percent, according to NIAAA. The health effects of drinking depend mainly on how much alcohol is consumed and how often, not on which liquor it is.

Getting Information and Support

two women job together down a waterfront path, wondering if tequila is a depressant

Understanding that tequila is a depressant can help you make informed choices about drinking, especially if you take medications that also slow the brain and body.

The Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 1-800-662-4357 is free and confidential, and anyone in a mental health or suicide crisis can call or text 988. For signs of alcohol overdose, call 911. Simple Path Recovery provides outpatient addiction treatment in Pompano Beach for adults.

This article is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Do not stop or change a prescribed medication without talking to your prescriber. If you are in crisis, call or text 988; for signs of overdose, call 911.

Sources

  1. Addicott MA, et al. The biphasic effects of alcohol: comparisons of subjective and objective measures of stimulation, sedation, and physical activity. Alcohol Clin Exp Res. 2007;31(11):1883-1890. doi:10.1111/j.1530-0277.2007.00518.x. https://pubmed.ncbi.nlm.nih.gov/17949393/
  2. National Institute on Alcohol Abuse and Alcoholism. What Is A Standard Drink? Updated December 2025. https://www.niaaa.nih.gov/alcohols-effects-health/what-standard-drink
  3. Centers for Disease Control and Prevention. Effects of Mixing Alcohol and Caffeine. May 15, 2024. https://www.cdc.gov/alcohol/about-alcohol-use/alcohol-caffeine.html
  4. National Institute on Alcohol Abuse and Alcoholism. Understanding the Dangers of Alcohol Overdose. Updated December 2025. https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/understanding-dangers-of-alcohol-overdose
  5. U.S. Food and Drug Administration. FDA requiring Boxed Warning updated to improve safe use of benzodiazepine drug class. September 23, 2020 (content current as of October 2, 2020). https://www.fda.gov/drugs/drug-safety-and-availability/fda-requiring-boxed-warning-updated-improve-safe-use-benzodiazepine-drug-class

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Cathy Bilotti - M.ED., LMHC - Clinical Director

Cathy Bilotti, M.ED., LMHC

Clinical Director

Cathy decided 10 years ago to switch gears and leave her family restaurant business to pursue a career she felt was more rewarding and aligned with her passion of helping others. Cathy received her master’s degree in mental health counseling from Florida Atlantic University and is a licensed mental health counselor in the state of Florida.

She has worked in the field for the past 8 years and has experience in treating both mental health and substance abuse. Cathy is passionate about creating a safe, trusting environment with her clients that promotes healing. Her desire is to explore the root of her client’s problems and how substance use became the solution to their issues.

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